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The 6.6-magnitude quake struck at 2152 local time (1552 GMT) on Sunday, destroying more than 100 buildings in the southern province of Osh.

Rescue workers are still searching for survivors under the rubble, the emergencies ministry said.

Destruction was concentrated in Nura, a village in the mountains close to the border with China.

Health officials said the remote location of the village was hampering rescue efforts.

"The picture we saw was frightening," Emergency Situations Minister Kamchybek Tashiyev was quoted as saying by AFP news agency.

"The village of Nura is fully destroyed, 100%, there are many injured."